Thursday, November 28, 2019

Love Shouldnt Hurt Essays - Abuse, Behavior, Human Behavior

Love Shouldn't Hurt Domestic Violence is emotional or physical abuse or the threat of physical abuse, used by one person in a relationship to gain control over the other person.(1) Rich, poor, Jewish, Christian, homosexual, heterosexual, abuse comes from all shapes and sizes. Domestic violence is the most prevalent cause for injury to woman in the United States. Often incidents of abuse start small with an abuser slowly taking control, as the relationship intensifies, the frequency as well as the intensity of the incidents also steadily increase. The incidents are then preceded with a phase in which the abuser may apologize, claim it will never happen again, express regret, promise to change, and/or blame their partner for what occurred. It is not easy for a person who is being abused to just walk away, and someone fleeing from their abuser will often return repeatedly before making a complete break. At the point in which a person is ready to walk away, they are normally battered, their life in danger, with no self-confidence, feeling they cannot live without their abuser. To a person who is not in an abusive relationship it is easy to tell someone being abused simply to walk away, but that person either doesn't know they are being abused, won't except it, or thinks it is their fault and they deserve it. Basically it is not as easy as it sounds. Domestic violence can take a number of forms, including: physical behavior such as slapping, punching, pulling hair or shoving, forced or coerced sexual acts or behavior such as unwanted fondling or intercourse, or jokes and insults aimed at sexuality, threats of abuse -- threatening to hit, harm or use a weapon on another, or to tell others confidential information, and psychological abuse -- attacks on self-esteem, controlling or limiting another's behavior, repeated insults and interrogation. When all is said and done, wife-beating results in more injuries requiring medical treatment than rape, auto accidents, and muggings combined.(2) Although on the surface domestic violence can appear to involve only the two parties of the abuser and their victim, the effects of abuse branch out to incorporate, indirectly all of society. It is not just a personal issue. Abuse goes outside the house, and affects every aspect of the victims life, because abuse is not about hitting the person, it is about controlling their lives. A child, by definition, is a person who is dependent upon adults and the environment for not only physical, but for emotional sustenance as well. This includes emotional warmth and nurture as well as protection from both external and internal threats to a child's sense of safety, self-esteem and well being. A parent and the home should provides a child with a safe space in which to experience their many complex and often intense emotions. Aggressive, passionate, sad or painful feelings arise in all human beings. The infant, toddler, and young child are helped by care taking adults to accept and tolerate frightening impulses and feelings. A child's idea of self worth and of belief in one's own goodness and in the general goodness of others -- is thus a fragile entity. When the adult surroundings are full of conflict, fear and p ain, a child's growth and emotional well-being are clearly jeopardized. There is a public education campaign about domestic violence currently being conducted on the New York City subway system. The poster used in the campaign has a picture of a child who is described as a highly sensitive recording device capable of detecting and remembering the abuse that occurs in his or her home. As the poster suggests, if tension, anger, and violence are present in the home, a child will know about it -- whether or not he or she has witnessed it directly and whether or not abuse is openly discussed. Regardless of how much effort has been made by adults to shield and protect a child by making sure that the violence takes place in private and by keeping it a secret, when a mother is being battered, a child becomes a victim too. The difference between the child and the adult victim is that the adult is, at least to some

Sunday, November 24, 2019

Healthcare Plans essays

Healthcare Plans essays The HMO-Secure Horizons plan is a Medicare Advantage HMO plan offering customers a model of healthcare requiring they select a local primary care provider responsible for overseeing and coordinating their general care (United Healthcare, 2006). If a patient signs up for this plan, they must first review a list of contracted doctors that work with the plan and work with contracted hospitals that participate in this HMO plan. Most patients are limited to care received from contracted doctors only, or doctors directly affiliated with the HMO network, unless an emergency arises. In this case, as in a case where you may be out of state, the plan will typically cover medical care received. Unfortunately this may mean plan participants have to change doctors if their doctor is not currently one that contracts with the Secure Horizons HMO Medicare plan. This can be a cause for concern and distress especially among the elderly, or individuals who have seen a doctor for an extended time and c reated a lasting relationship. Patients enrolling in the Secure Horizons HMO have a choice of plan coverage, some of which offer prescription drug coverage, recognized by many as Part D coverage. This type of coverage proves increasingly important for older or elder citizens who typically have more prescription needs than younger patients (Okunade, 2006). Nurses and doctors play an important role in educating consumers about their health care coverage and prescription drug plans, especially considering most patients are not confident of the information they receive directly from the company websites they visit to find information on their healthcare provisions (Hong, 2006). Most patients who sign with a healthcare plan as this must lock in for a minimum amount of time and must pay a deductible, one that is often high in order to keep monthly premiums low. When the Medicare Part D plan was introduced, many believed parti ...

Thursday, November 21, 2019

Alienation Assignment Example | Topics and Well Written Essays - 500 words

Alienation - Assignment Example It implies that the products (or services) made defines workers.The higher the valuation of the product, the less the worker is valued implying that workers contributing to economic growth benefit least. Marx explains the controversy between human investment and expected gains, whereby workers receive the least from the economic advancement compared to property owners, because of capitalism influence (Marx 70). Marx’s assertion that â€Å"The worker becomes a slave of his object† implies a condition of dependence by a worker because the object product determines labor. Enslavement is because devaluation of workers, thereby compelling them to provide labor consistently. The concept of alienation has various effects in different societal settings, which involve both communist and capitalist. Communist and capitalist societal settings contrast each other. The communist society helps to streamline the inter-relation between labor and product through common delegation of resources (Marx 66). Contrary to communism, capitalist uphold the existence of private property, which is the apex of alienation (Marx 79). Private property is an ultimate idea in capitalistic societies. Ac cording to Marx, private property advocates the existence of inhuman power (100). Inhuman power concerning alienation involves the exploitation of the work force by the wealthy. Resource delegation in such cases of capitalism favors the wealthy who enjoy other people’s investments. Marx maintains that capitalism causes people to be self-centered making them regard others as useful entities for their success (101). He argues that the human activity in the absence of alienation is normal due to the lack of abstraction (74). The product and labor value have inherent relations because of lack of devaluation production processes. The products’ nature defines human activity. However, the product in a

Wednesday, November 20, 2019

The impact of corporate social responsibility on organisational Essay

The impact of corporate social responsibility on organisational effectiveness - Essay Example The article also focuses the value of those components for the stakeholders of the companies. The article further segregates the ethical component of the corporate social responsibility in order ton relate it to some major ethic management approaches, which include moral, immoral, and amoral managements. I think the author of the article has written the article in a well-structured format. The article is easy to read, as well as easy to understand for the readers. All sections of the article are well-organized and provide a clear view of the author’s thoughts. The article is also based on the logical facts about the significance of corporate social responsibility in achieving higher levels of productivity. The author has also focused on ethical and moral; management approaches which is also an important part of the article. The article relates to our research in a way that it makes us aware of ways executives can use corporate social responsibility to fulfill their responsibilities that they owe towards their shareholders and other competing groups. This article focuses of how managers can use finance to make the organization socially responsible and responsive. Of course, finance always play a critical role in almost every organizational matter and corporate social responsibility is no exception. The author puts his views on the criticism regarding corporate social responsibility that it is of little significance of companies as it used mostly as a tool of enhancing public relations. The article reveals that many organizations actually incorporate corporate social responsibility in their daily business activities but are unaware of the way to report that responsiveness in a formal way. Moreover, the article focuses on how accountants can use their knowledge in developing CSR and reporting the metrics to show the organizational involvement in social responsiveness. I have found the article to be very useful in learning the role of

Monday, November 18, 2019

The Commission and the Crime Committed Case Study

The Commission and the Crime Committed - Case Study Example The policy on the corruption being committed in the case of Former State corrections Chief James Crosby Jr. will be reviewed. The policy involved in this case is the Federal law about the corruption of a government official. Even though this policy was not clearly defined, the case of Crosby was able to pursue. Based on the evidenced presented against Crosby it was clear that he committed corruption by taking kickbacks from the prison vendor. The only confusing about this case is that what policy or Federal law was being violated. The official being convicted of corruption means that he committed the Chapter 839 of the 1999 Florida Statutes. Chapter 839 - The Offences by Public Officers and Employees Chapter 839 of the 1999 Florida Statutes under title XLVI is the Offences by Public Officers and Employees. (1) The "Official Misconduct" as defined in Chapter 839.25, means the commission of the following act by a public servant, with corrupt intent to obtain a benefit for himself or herself or another or to cause unlawful harm to another: Knowingly falsifying, or causing another to falsify, any official record or official document. (2) "Corrupt" means done with knowledge that act is wrongful and with improper motives. (3) Official misconduct under this section is a felony of the third degree, punishable as provided in section 775.082 Penalties, and section 775.083 Fines. The charge of Corruption to Crosby maybe questionable but it appears to be legal and justifiable. The force removal of Crosby in position is the result of the violation of Chapter 839.04County officers not to speculate in county warrants or certificates.- (1) Any... This report is to be presented in order to help the commission to revise and reviewed the policy involved in cases. Ethical issues involve are important to discuss to avoid misunderstanding and further questioning on the cases. As the ethics laws are â€Å"strictly construed,† because they are penal in nature, virtually any ambiguity in a statute will be construed in favor of the public official. Therefore, the ethics laws must be written to specifically address ambiguities that have arisen. In addition, meaningful enforcement of the laws is enhanced when the laws clearly identify appropriate standards of conduct. Federal law prohibits federal employees from leaving their public position and then participating in a matter in a way that is adverse to the former agency where the employee had participated personally and substantially in the employee’s official capacity. Attorneys are subject to a similar restriction, under Bar regulations. The Code of Ethics should cover the same situations. Otherwise, for example, a Department of Revenue employee involved in a taxpayer case could quit the Department and work for the taxpayer, against the Department, on the same case.

Friday, November 15, 2019

Method Development for Protein Detection

Method Development for Protein Detection Binding-induced and label-free colorimetric method for protein detection based on binding-induced DNA hybridization and DNAzymebased signal amplification INTRODUCTION In diagnosing the early stage of a disease or pathological condition, proteins, especially those associated with cancers, are of great importance because they are the molecular machinery of life.[BB2013-AM-3, 1,2] Enzyme-linked immunosorbent assay (ELISA) is the most commonly used method for protein detection.[PD-3,1,2] Unfortunately, this antibody-based assay requires a long incubation periods and long assay times with the involvement of multiple washing steps.[PD-5,1,2] Additionally, it is faced with the challenges of insufficient sensitivity and limited dynamic range.[PD-4, 5,6,7] As an alternative to the antibody-based assay, aptamer-based assays have gained tremendous attention recently.[PD-4,9-11] Aptamers are single stranded DNA or RNA oligonucleotides selected from random sequence nucleic acid libraries through an in vitro selection process termed systematic evolution of ligands by exponential enrichment (SELEX).[PD-6,4-6] They possess high affinity and good selectivity for s mall molecules, proteins or other targets.[BB-11,20-22] Compared to antibodies, aptamers exhibit obvious advantages including a better stability for long-term storage, a rapider preparation by chemical synthesis in large quantity, and the flexible modification with a variety of functional groups.[PD-4, BB-11,23,24] Some aptamer-based amplified detection assays for protein have been developed in the past two decades, such as the polymerase chain reaction (PCR), rolling circle amplification (RCA), strand displacement amplification (SDA) and ligase chain reaction (LCR). [BB-AM-3] Although these amplified assays greatly enhance the sensitivity of protein detection, they are usually time-consuming and too complicated. Therefore, the amplified detection of protein is still challenging in bioanalytical chemistry.[BB2013-AM-3] Deoxyribozymes (DNAzymes) are artificial nucleic acids, which are isolated from in vitro selection. [DM-5] Similar to traditional protein enzymes, they exhibit high catalytic hydrolytic toward specific substrates, while they possess higher thermal stability that can be denatured and renatured formanycycles without losing catalytic activities.[DM-4] This obvious advantage makes DNAzymes ideal biocatalysts for achieving signal amplification in biological applications.[DM-4] An important development in the DNAzyme field is the discovery of the G-quadruplex DNAzyme.[DM-9,9] The G-quadruplex sequences can associate with a cofactor, hemin, to form peroxidase-mimicking DNAzymes to catalyze the H2O2-mediated oxidation of 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) to a green-colored product ABTS†¢Ã¢Ë†â€™ or enhance the chemiluminescence of the luminol-H2O2 system.[DM-6,25, DM-5,44] With this main advantage, G-quadruplex DNAzyme has been employed to develop many colorime tric, chemiluminescent or fluorescent sensing platforms for the detection of proteins, DNA and other biomolecules.[DM-9,14,DM-2,34-37] Recently, Willners group reported an enzyme-free amplified detection platform based on the hemin/G-quadruplex horseradish peroxidase (HRP)-mimicking DNAzyme.[AC2012-2] This strategy is quite successful, while the target detection is limited to DNA, and the detection of protein represents another challenge. In this work, taking the advantages of the high selectivity and affinity of aptamers and the HRP-mimicking DNAzyme amplification strategy, we designed a new binding-induced and label-free ultrasensitive colorimetric method for amplified detection of protein. As a proof of principle, human ÃŽ ±-thrombin and its two aptamers, Apt29 and Apt15, are used. In this sensing system, Apt29 and Apt15 are integrated into the proximity probes as recognition elements for the thrombin. These two proximity probes hybridize with each other stably only when both of them bind to the thrombin simultaneously.[BB2013-AM-3] The binding-induced hybridization duplex triggers an autonomous cross-opening of the two functional hairpin structures. And this leads to the formation of a variety of hemin/G-quadruplex DNAzymes. The DNAzymes catalyze the oxidation of ABTS, generating a green colorimetric signal, which can be monitored simply by a spectrophotometer. [DM-3,29,30] This binding-induced and DNAzyme-based s ignal amplified method has a great potential for protein detection. [BB2013-AM-3] In addition, since various recognition elements might be fused, this method can be further extended to sensitive detection of other proteins.[DM-4] EXPERIMENTAL SCETION Materials and Reagents. All DNA oligonucleotides were purchased from Genscript (Jiangsu, China). The oligonucleotides were PAGE-purified and diluted in pH 7.4, 20 mM Tris-HCl buffer solution (containing 100 mM NaCl, 20 mM KCl, and 2 mM MgCl2) to give stock solutions of 100 ÃŽ ¼M. Before use, two hairpin structures were heated to 95à ¢Ã¢â‚¬Å¾Ã†â€™ for 5 min, and slowly cooled down to room temperature. Human ÃŽ ±-thrombin (Tb), bovine serum albumin (BSA), and human serum albumin (HSA) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Hemin, [tris(hydroxymethy-l)aminomethane] (Tris), 4-(2-hydroxyethyl)piperazine-1-ethanesulfonic acid sodium salt (HEPES), 2,2-azino-bis(3-ethylbenzothiozoline-6-sulfonic acid) (ABTS), and H2O2 were purchased from Aladdin Reagents (Shanghai, China). A hemin stock solution (1 mM) was prepared in dimethyl sulfoxide (DMSO) and stored in the dark at −20  °C. All other chemicals were of analytical grade and were used without further purification. All solutions were prepa red using double-distilled water, which was obtained through a Milli-Q purification system (Billerica, MA, USA). Absorbance Measurements. Absorbance measurements were performed under room temperature using a TU-1901 UV−visible spectrophotometer (Beijing Purkinje General Instrument Co, Ltd., China). Kinetic data were recorded at the wavelength of 420 nm every 5 s during the first 5 min of the reaction. The absorption spectra of the solution was measured in the wavelength range from 390 to 490 nm. Procedure for Thrombin Assay. The experiments were performed in 50 ÃŽ ¼L of Tris-HCl buffer (20 mM Tris-HCl, pH = 7.4, 100 mM NaCl, 20 mM KCl, 1 mM MgCl2) containing 200 nM P1, 200 nM P2 and varying concentrations of Tb. The mixture was first incubated for 30 min at room temperature to allow complete binding. Next, 25 ÃŽ ¼L of 2 ÃŽ ¼M H1 and 25 ÃŽ ¼L of 2 ÃŽ ¼M H2 were added and incubated for 6 h at room temperature. Then, 20 ÃŽ ¼L of 2 ÃŽ ¼M hemin and 240 ÃŽ ¼L of HEPES buffer (25 mM HEPES, pH= 7.4, 200 mM NaCl, 20 mM KCl, 0.05% Triton X-100, 1% DMSO) were added, and allowed to incubate for 1 h at room temperature. Finally, 30 ÃŽ ¼L of ABTS and 10 ÃŽ ¼L of H2O2 were added to the mixture to give the final concentrations of 2 mM and 2 mM, respectively. The resulting samples were tested with a UV−vis spectrometer. RESULT AND DISCUSSION Design strategy for human ÃŽ ±-thrombin detection The sequences of the oligonucleotides used in this work were listed in Table 1. It consists of two proximity probes (P1 and P2) and two hairpin structures (H1 and H2). Both proximity probes P1 and P2 consist of four domains. Domain I includes two different thrombin aptamers, Apt29 (29 mer) and Apt15 (15 mer). The Apt29, orange domain of P1, binds to the heparin-binding site and the Apt15, skyblue domain of P2, binds to the fibrinogen-binding site of thrombin, resulting in proximity. Domain II (black) consists of a poly-T sequence that is designed to reduce the effect of steric hindrance induced by thrombin. Domain III (pink) is designed to have only 6 complementary bases, so that two proximity probes P1 and P2 cannot form a stable duplex without the target protein at room temperature. Domain IV (blue) is the key domain for binding-induced DNAzyme-assised signal amplification. By using two functional hairpin structures, the recognition of domain IV could trigger-on the hybridization c hain reaction that led to DNAzyme chains consists of the hemin/G-quadruplex HRP-mimicking DNAzyme. Hairpin structure H1 is functionalized at its 5 end with three-fourths of the G-quadruplex sequence, domain V (green), which is linked to the programmed sequences VIII (red) and VII (blue). One-fourth of the G-quadruplex sequence, domain VI (green), is extended at the 3 end of the hairpin H1. Hairpin structure H2 is functionalized at its 5 and 3 ends with one-fourth of the G-quadruplex (domain VI) and three-fourths of the G-quadruplex (domain V) sequence, respectively. Programmed sequences of domains VII and VIII in hairpin H2 are complementary to domains VII and VIII in hairpin H1, respectively. Both four domains in hairpin H1 and H2 are incorporated into a stable hairpin configuration in an initially locked format by hybridizing with their partially complementary sequences. It is noteworthy that sequence V is partially hybridized with domain VII in hairpin H1 or VIII in hairpin H2, w hich prevents the self-assembly of the active hemin/G-quadruplex DNAzyme. Principle of binding-induced DNAzyme-assisted amplification strategy for human ÃŽ ±-thrombin detection The working principle of human ÃŽ ±-thrombin detection is illustrated in Scheme 1. In the absence of thrombin, domain III in P1 and domain III in P2 will not associate since the complementary sequences (6 nt) are too short to promote efficient hybridization. When the target thrombin is introduced into the system, domain I in P1 and P2 bind to the protein simultaneously, resulting in domain III and III sufficiently close and to hybridize to each other to form a stable P1-Tb-P2 duplex, step 1. [BB2013-AM-3] Once the P1-Tb-P2 duplex forms, it associates with the stem region of H1, domain VII, leading to an opening of H1. This opening of H1 results in the release of the single-stranded domain VIII and the conserved three-fourths of the G-quadruplex (domain V), step 2. The released domain VIII then hybridizes with domain VIII of the stem in H2, and opens H2 using the strand displacement principle, step3. Subsequently, the liberated domain VII in H2 cross-hybridizes with H1 by hybridizatio n of domain VII to domain VII in H1, resulting in two G-quadruplex subunits (domain V and VI) sufficiently close and to self-assemble into a G-quadruplex structure, step 4. [AC2012-4] In the process of this autonomous cross-opening of H2 and H1, strand displacement can be repeated continuously, generating numerous G-quadruplex structures. In the presence of hemin, the resulting catalytic hemin/G-quadruplex peroxidase-mimicking DNAzymes catalyze the H2O2-mediated oxidation of the colorless ABTS2− to green-colored ABTS†¢Ã¢Ë†â€™. Detection of thrombin in human serum To further demonstrate the feasibility of the proposed method in real bioenviroments, we performed the detection of thrombin in human serum. [AC2013-4] Three concentrations of thrombin (10 pM, 100 pM, and 1000 pM) were spiked into 10-fold diluted human serum. [ZK-CC-1] Figure 4 shows the time-dependent absorbance changes of ABTS†¢Ã¢Ë†â€™ in response to different concentrations of thrombin. [AC2014-6] In logarithmic scales, the absorbance value exhibits a linear correlation with thrombin concentration over a range of 3 orders of magnitude from 10 pM to 1000 pM (inset of Figure 4B). [AC2012-12] The result indicated the potentiality of the proposed method for protein detection in real biological samples. [AC2013-4] Conclusions In conclusion, we have developed a binding-induced and label-free colorimetric method for protein detection based on binding-induced DNA hybridization and DNAzyme-assisted signal amplification. This method does not require any modification of DNA and involve any protein enzyme, which makes it technically label-free, enzyme-free and very cost-effective. Furthermore, the present approach uses a simple separation-free procedure in which the assay is conducted in a homogeneous solution.[AC2014-3] In addition, due to the excellent specificity of two proximity probes to the thrombin and the ingenious design of two hairpin structures,[AC-EA-2] this method exhibits a high sensitivity for thrombin detection, with a low detection limit of 2.5 pM. More importantly, this method can be extended to sensitive detection of other proteins by simple changing the aptamer sequences of the two proximity probes. To sum up, this simple and cost-effective colorimetric signal amplified method has great poten tial to be used as a universal tool for ultrasensitive analysis of thrombin or other proteins in serum and supply valuable information for biomedical research and clinical diagnosis.[ZK-CC-1]

Wednesday, November 13, 2019

Aids and Society :: HIV Social Issues Health Essays

Aids and Society Aids and Society The number of newborns infected by vertical transmission of the human immunodeficiency virus is increasing as the prevalence of HIV-positive women increase within the United States. It is estimated that while seven thousand HIV-positive women become pregnant each year, between one thousand and two thousand of their newborns will be HIV-positive. This research paper will concentrate on the transmission of the human immunodeficiency virus from mother to child, the benefits of drugs intervention, and whether or not the HIV-screening process of pregnant women should remain voluntary or become mandatory. The HIV-virus has proven that it is not a disease to be taken lightly or ignored. I chose this topic because I want to be informed about the virus and its rate of vertical transmission so that I will be able to inform others about such ethical topics: Does the baby have rights and should a pregnant women be denied her right to privacy with respect to HIV? Data shows that AIDS is now increasing faster among females than males, with women accounting for seven percent of cases in 1985 and nineteen percent in 1995. The incidences of HIV-positive heterosexual women have risen dramatically over the past decade, and AIDS is now the third leading cause of death among women ages twenty-five to forty-four. The one thing that all of these women have in common is that they all are of child bearing age. Consequently, the incidences of HIV-positive newborns have also increased. As mentioned previously, about seven thousand HIV-infected women give birth each year, and about twenty-five percent of their babies are HIV-positive. â€Å"Maternal transmission accounted for ninety-two percent of all new AIDS cases reported in children in 1994†(Davis15). A major breakthrough in drug intervention began in February 1993. The AIDS Clinical Trials Group administered a double-blinded, randomized, placebo-controlled study of zidovudine, also known as AST. Four hundred s eventy-five women were enrolled in the study. These women were randomly assigned to one of two groups. One group received zidovudine while the other, the control group, received a placebo. The administration of either zidovudine or placebo began in the second trimester of pregnancy and continued through labor. For six weeks after birth, the babies received the same treatment as the mothers in a syrup form. Because it was a double-blinded study, neither the researchers nor the patients knew who was actually receiving the zidovudine.

Sunday, November 10, 2019

On Boy Trouble Essay

â€Å"On Boy Trouble† Essay In the essay, â€Å"On Boy Trouble† by Margaret Wente, many points were introduced to the readers. Margaret Wente lures the readers to her article by using an opening sentence such as â€Å"They are tormented by unattainable ideals,† (pg. 427). Wente attracts the readers by exercising her writing abilities and using effective and efficient words and phrases. Also, the use of allusions are very effective. Margaret Wente’s charismatic style of writing is very helpful to the readers in a way that differs from most other writers. With Wente’s style of writing, the reader does not get bored or sidetracked while reading her craftsmanship. Margaret Wente opens up about her research on the male society. She proves a somewhat non-biassed point about what type of torture and anguish most adolescent males go through in order to â€Å"fit in†. Wente expresses her points in a very effective manner by issuing facts, and examples, that seduces the reader into reading more. This is a magnificent piece of writing and is easy to read. One who is not very eager to pick up a highly intellectual piece of writing because of being in fear of becoming lost or confused while reading, should not worry about this piece. Wente does not use too many â€Å"big† words in her essay, but does include some very effective ones. The article, â€Å"On Boy Trouble†by Margaret Wente is a highly educational piece of writing, that tests the brain power of the reader, but does not stress it. Firstly, Wente’s use of effective words are one forceful way to attract the reader. Margaret Wente used such words as â€Å"psychological debilities†, â€Å"victims du jour†, â€Å"excruciating†, and â€Å"an orgy of introspection†. These words contribute to the success of her article. When a reader sees these types of words, they are immediately attracted to the piece and feel that the writer is highly intellectual. Words like â€Å"psychological debilities† are two highly intelligent words that would normally only be used by master scholar’s, or a philosopher of some sort. Words like these contribute to the effectiveness of the writing piece and it almost dares the reader to read further. In addition, a high vocabulary is very necessary for the author to possess in order to have an effective essay. The author’s choice of words, or diction, is a great way to get a point across to the readers, or the viewers. If a writer wrote a n article at a grade 5 level, the readers would most likely lose interest fairly quickly. The more intellectual the writer  seems, the more the readers will trust the writer, and listen to the writer, and understand the writer. Secondly, Wente’s charismatic style of writing keeps the reader involved in the article. Wente’s sense of knowledge and understanding about what a typical adolescent male goes through is simply amazing. The way the writer informs the reader of this topic is astounding. The way she states her ideas and beliefs are dumbfounding because of how easily she explains everything by backing them up with facts and examples. While explaining what an adolescent males has to face in a physical aspect of being â€Å"buff† and in shape, she does so in a very informative, and somewhat comedic manner. Wente says that a teenage male is being stereotyped into having to have arms like G.I. Joe. Wente states, â€Å"G.I. Joe, whose biceps, if life-sized, would measure an astonishing 32 inches† (pg. 428). Obviously, that is a comedic way of getting her point across. Next, when Wente said, â€Å"Everyone else – nerd, geek, Goth, or plain, unlabelled loser – is subject to emotional abuse whose scars may last a lifetime.† (pg. 429), she is so close to reality, it is scary. In addition, sometimes it is good to inform the reader without beating around the bush. The conclusion to the essay was especially effective because it makes the reader feel that Margaret Wente is actually talking to them, one-on-one. Wente stated, â€Å"Either way, consider yourself warned. Your son needs help, and lots of it†. It is good to just say what is on one’s mind straight up, without glamorizing things. Lastly, the use of allusions also contributed to the article. Margaret Wente referred to many different types of books in her essay. Wente spoke about Susan Faludi’s most recent book, Backlash, and her upcoming book, Stiffed. Also, Margaret Wente mentioned many other book titles when she said, â€Å"Books with titles like Real Boys, Raising Cain, Wonder of Boys, and Lost Boys are flying off the shelves† (pg. 428). â€Å"Forget Reviving Ophelia. It was Hamlet who had the real problems† (pg. 428) was also an allusion. Allusions don’t usually contribute to an essay in such a way that this does. Allusions are just a way to help the reader’s understanding and a way to help the reader’s point get across. On the other hand, an allusion usually only appears in an essay once or twice, if any, but this essay was more effective because of  the massive allusions involved. Margaret Wente also made reference to the masterpiece movie, Lord of the Flies. A llusions can be extremely effective if they are used properly. In conclusion, Margaret Wente’s style of writing is highly educational and requires the reader to think, but only to a certain degree. Margaret Wente is a literature genius and obviously knows her work. Her research of adolescent males is astonishing, and pretty much unbelievable. One could be almost positive that most adolescent males may not be as aware of what is happening to them as Margaret Wente is. Her skills in writing are obviously exercised in this piece. An adolescent male does go through a lot of pain and suffering in their teenage years in order to try to mould themselves into this ridiculous stereotype. Therefore, in order to be a successful writer, one must know what they are talking about, in order to inform others.

Friday, November 8, 2019

Biography of Rem Koolhaas, Dutch Architect

Biography of Rem Koolhaas, Dutch Architect Rem Koolhaas (born November 17, 1944) is a Dutch architect and urbanist known for his innovative, cerebral designs. He has been called a modernist, a deconstructivist, and a structuralist, yet many critics claim he leans toward humanism; his work searches for a link between technology and humanity. Koolhaas teaches at the Graduate School of Design at Harvard University. Fast Facts: Rem Koolhaas Known For: Koolhaas is an architect and urbanist known for his unusual designs.Born: November 17, 1944 in Rotterdam, NetherlandsParents: Anton Koolhaas and Selinde Pietertje RoosenburgSpouse: Madelon VriesendorpChildren: Charlie, TomasNotable Quote: Architecture is a dangerous mixture of power and impotence. Early Life Remment Lucas Koolhaas was born in Rotterdam, Netherlands, on November 17, 1944. He spent four years of his youth in Indonesia, where his father, a novelist, served as cultural director. Following in the footsteps of his father, the young Koolhaas began his career as a writer. He was a journalist for the Haase Post in The Hague and later tried his hand at writing movie scripts. Koolhaass writings on architecture won him fame in the field before he had even completed a single building. After graduating in 1972 from the Architecture Association School in London, Koolhaas accepted a research fellowship in the United States. During his visit, he wrote the book Delirious New York, which he described as a retroactive manifesto for Manhattan and which critics hailed as a classic text on modern architecture and society. Career In 1975, Koolhaas founded the Office for Metropolitan Architecture (OMA) in London with Madelon Vriesendorm and Elia and Zoe Zenghelis. Zaha Hadid- a future winner of the Pritzker Architecture Prize- was one of their first interns. Focusing on contemporary design, the company won a competition for an addition to the Parliament in The Hague and a major commission to develop a master plan for a housing quarter in Amsterdam. The firms early work included the 1987 Netherlands Dance Theater, also in The Hague; Nexus Housing in Fukuoka, Japan; and Kunsthal, a museum built in Rotterdam in 1992. Delirious New York was reprinted in 1994 under the title Rem Koolhaas and the Place of Modern Architecture. The same year, Koolhaas published S,M,L,XL in collaboration with the Canadian graphic designer Bruce Mau. Described as a novel about architecture, the book combines works produced by Koolhaass architectural firm with photos, plans, fiction, and cartoons. The Euralille Master Plan and Lille Grand Palais on the France side of the Channel Tunnel were also completed in 1994. Koolhaas also contributed to the design for the Educatorium at the University of Utrecht. Koolhaass OMA completed Maison Bordeaux- perhaps the most famous house built for a man in a wheelchair- in 1998. In 2000, when Koolhaas was in his mid-50s, he won the prestigious Pritzker Prize. In its citation, the prize jury described the Dutch architect as that rare combination of visionary and implementer- philosopher and pragmatist- theorist and prophet. The New York Times declared him to be one of architecture’s most influential thinkers. Since winning the Pritzker Prize, Koolhaass work has been iconic. Notable designs include the Netherlands Embassy in Berlin, Germany (2001);  the Seattle Public Library in Seattle, Washington (2004);  the CCTV Building in Beijing, China (2008);  the Dee and Charles Wyly Theatre in Dallas, Texas (2009);  the Shenzhen Stock Exchange in Shenzhen, China (2013);  the Bibliothà ¨que Alexis de Tocqueville in Caen, France (2016);  the Concrete at Alserkal Avenue in Dubai, United Arab Emirates (2017); and his first residential building in New York City at  121 East 22nd Street. A few decades after founding OMA, Rem Koolhaas reversed the letters and formed AMO, a research reflection of his architecture firm. While OMA remains dedicated to the realization of buildings and masterplans, states the OMA website, AMO operates in areas beyond the traditional boundaries of architecture, including media, politics, sociology, renewable energy, technology, fashion, curating, publishing, and graphic design. Koolhaas continued to do work for Prada and in the summer of 2006, he designed the Serpentine Gallery Pavilion in London. Visionary Pragmatism Koolhaas is known for his pragmatic approach to design. The McCormick Tribune Campus Center in Chicago- completed in 2003- is a good example of his problem-solving. The student center is not the first structure to hug a rail- Frank Gehrys 2000  Experience Music Project (EMP) in Seattle has a monorail that goes directly through that museum, like a Disney extravaganza. The Koolhaas Tube (made of corrugated stainless steel) is more practical, though. The city train connects Chicago with the 1940s campus designed by  Mies van der Rohe. Not only was Koolhaas thinking about urbanist theory with the exterior design, but before designing the interior he set out to document student patterns of behavior to create practical pathways and spaces inside the student center. This was not the first time Koolhaas had played with trains. His Master Plan for Euralille (1989–1994) transformed the northern city of Lille, France, into a tourist destination. Koolhaas took advantage of the completion of the Channel Tunnel, using it as an opportunity to remake the city. Of the project, he said: Paradoxically, at the end of the 20th century, the frank admission of the Promethean ambition- for example, to change the destiny of an entire city- is taboo. Most of the new buildings for the Euralille project were designed by French architects, except for Congrexpo, which Koolhaas himself designed. Architecturally, Congrexpo is scandalously simple, it says on the architects website. It is not a building that defines a clear architectural identity but a building that creates and triggers potential, almost in an urbanistic sense. In 2008, Koolhaas designed the China Central Television Headquarters in Beijing. The 51-story structure looks like an enormous robot. Yet The New York Times writes that it may be the greatest work of architecture built in this century. These designs, like the 2004 Seattle Public Library, defy labels. The Library appears to be made up of unrelated, disharmonious abstract forms, having no visual logic. And yet the free-flowing arrangement of rooms is designed for basic functionality. Thats what Koolhaas is famous for- thinking forward and backward at the same time. Designs of the Mind How are we to respond to structures with glass floors or erratically zigzagging stairs or shimmering translucent walls? Has Koolhaas ignored the needs and aesthetics of the people who will occupy his buildings? Or is he using technology to show us better ways to live? According to the Pritzker Prize jury, Koolhaass work is as much about ideas as it is buildings. He became famous for his writings and social commentary before any of his designs was actually constructed. And some of his most celebrated designs remain on the drawing board. Koolhaas has said that only 5% of his designs ever get built. Thats our dirty secret, he told Der Spiegel. The biggest part of our work for competitions and bid invitations disappears automatically. No other profession would accept such conditions. But you cant look at these designs as waste. Theyre ideas; they will survive in books. Sources â€Å"Jury Citation: Rem Koolhaas.† The Pritzker Architecture Prize.â€Å"IIT McCormick Tribune Campus Center.† OMA.Oehmke, Philipp, and Tobias Rapp. â€Å"Interview with Star Architect Rem Koolhaas.† Spiegel Online, Der Spiegel, 16 Dec. 2011.Ouroussoff, Nicolai. â€Å"Koolhaas, Delirious in Beijing.† The New York Times, The New York Times, 11 July 2011.

Wednesday, November 6, 2019

Stephen Leackock essays

Stephen Leackock essays Stephen Leacock led a fascinating life. He lived on various continents throughout his childhood, wrote 35 books, and won many awards. In this essay I will discuss his life, the awards and honours he received, and the amazing number of books he produced. Stephen endured difficult periods during his lifetime. His parents, Peter and Agnes Leacock, had a large family, which they had trouble adequately supporting. They tried farming in many different places including South Africa and Kansas. In 1876 Peter took his family to Sutton, Ontario. In his unfinished autobiography, The Boy I Left Behind Me, Leacock said that our farm with its buildings was, I will say, the damnedest place I ever saw (p. 58 (taken from quote from government web site)). Stephen and his 10 other sibling didnt have a comfortable life on the farm, with the horrific stench of the barn, the horrible coldness of the farm house, and his single miserable candle to study by. His mother was determined to give her kids the best education possible so she took them out of the public school system and home schooled them. She carried the burden of their education herself until a tutor named Harry Park came along. After Stephens father deserted the family, Agnes was left to care for their eleven children as well as run the farm. In 1882 Stephen enrolled in Upper Canada College. He was an excellent student; he was even the editor of the college newspaper, The College Times. In 1887 he graduated at the top of the school, and returned home to find that his father, a drunk and penniless man at this point, had come back. However, the following summer he found some money and left again. He never returned, living out the rest of his days in Nova Scotia. He never saw his wife or children again, and lived with his common-law wife until his death in 1940. Stephens real interest was political science, which he studied at the Uni ...

Monday, November 4, 2019

Phuket thailand Essay Example | Topics and Well Written Essays - 750 words

Phuket thailand - Essay Example Phuket, Thailand’s largest island experienced the 9.3 earthquake shock which sent the Andaman Wave to the island’s coastline. Considered the third worst in history, the tsunami waves rose up to 10 meters high and created severe destruction on the six provinces along the Andaman coastal strip, namely: Phang Nga, Krabi, Phuket, Ranong, Satun and Trang. At least 250 people were recorded injured and maimed with scores of others dead including tourists. There was massive destruction of property ranging from hotels, houses to vehicles and other properties worth millions. Almost all west coast beaches like Karon, Kamala and Patong were completely destroyed to the ground with few deserted buildings standing. In addition, the effects of the tsunami were devastating because it greatly affected the tourism industry in the island. On the other hand, the cause of the tsunami arised as a result of the corrison of the Indo-Australian plates. The Indo plate is lower while the Australia n plate is bigger. The impact led to a massive earthquake that triggered the tsunami disaster in the region and entire southeast Asia. Apart from the devastating tsunami, Phuket has also been experiencing earthquakes regularly. On April 2012 the island was affected by a 4.3 magnitude earthquake that led to eviction of people from the coastal and lower regions to higher grounds to protect them from the earthquake. The quake which originated from the Klong Marui fault line spanned to other provinces like Phang Nga, Krabi and Surat Thani. No deaths or injuries were reported, however at least 30 houses sustained cracks in Tambon Si Sunthon region (Wipatayotin, 2012). Moreover, another earthquake of a 6.5 magnitude occurred in Phuket island but no tsunami alerts were issued after the 2004 tsunami. The 6.5 magnitude earthquake was confirmed by officials to the north of Aceh. Earthquakes in Phuket

Friday, November 1, 2019

NFL Lockout and the Fans Research Paper Example | Topics and Well Written Essays - 1250 words

NFL Lockout and the Fans - Research Paper Example The lockout has led to uncertainties about the game of football which is eagerly awaited by the fans. In the war between the owners and the players, the ultimate burden is borne by the potential audience and other fans who have invested in products and services related to the sport. Before understanding the problem it is important to understand the significance of the ‘Final League Year’ that is 2010. In this year salary caps would not exist but there will be noteworthy restrictions of the lessening of players’ benefits. After this year the club will be free from its commitment to finance the different programs such as second career savings, severance and performance based pay etc. The payment made by the league for funding of such plans comprise of above $10 million for each club. The problem has culminated mainly into that of disputes between workers and employers. After the 1974 season this occurred again when the season’s sport was awaiting a halt. The District Court of US instructed the league to operate again. But without the CBA the confused persists and there are no ceilings or floor of payments and no benefit schemes. The scheduled game between Chicago Bears and the Tampa Bay Buccaneers at Wembley Stadium of London lie challenged especially if the problem is not resolved by September 8, 2011 (Battista). A review of the major concerns which preside over the lockout points out the disagreement on the division of $9.3 billion annual revenues between the two parties (league owners and the players). The players believe themselves to be major contributors to the game and the success of the league. They help the owners become rich. The owners on the other hand were more obsessed with the money they saw flowing in and did not ant to spend a substantial part on the players’ benefits. They believe it is more important to spend the money on stadiums and other infrastructures rather than submitting to their obligation in providing financial securities to the players. Also the owners might be blamed for paying less and venturing to make them play more games a season. One of the ethical issues concerns the players’ access to financial information which has been restricted by the owners (Maske). Till now the advantages stood in favor to the players but now they are inclined towards the owners who have the upper hand or dominating position. The court granted the league their original request for a temporary stay of order in April. After a month’s discussion the league made a second proposal to end the deadlock. The players were initially reluctant especially after the decision of Nelson but at present they have little option but to take the proposal of the league seriously. However the season 2011 is still not confirmed (Wilson). At this juncture, Bryant observes that the fans have learned the lesson, â€Å"those who own the teams, the commissioner who runs the league and, to a far lesser extent, the players who run the routes, sack the quarterbacks and score the touchdowns have so little perspective that they believe their inability to divide the $9 billion is, in the real world, important. We all know better.† (Bryant) Both the sides need to respect the people who spend their money buying tickets and sport